Adéla Galandáková (PhD, Ing.) (born Zdařilová)
Department of Medical Chemistry and Biochemistry
Hněvotínská 3
775 15 Olomouc, Czech Republic
e-mail: galandakova.a@seznam.cz
tel: +420 585 63 2325
Research Topics:
- Biological activity of natural substances, plant extracts (in vitro and in vivo), silver and gold nanoparticles; antioxidant and anti-inflammatory activity; metabolic transformation; DNA damage; influence of joint fluid composition on lubricating film formation in total hip arthroplasty.
- Cytotoxicity, inflammation, biological fluid, tribology
Position:
2005 – 2009
Researcher, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University Olomouc
2009 – present
Assistant Professor, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University Olomouc
2013 – 2015
Junior researcher, Institute of Molecular and Translatione Medicine, Palacký University Olomouc
2013 – 2015
Science analyst-diagnosticians, Orthopaedic Clinic, University Hospital Olomouc (part-time job)
2014 – present
Technical co-worker, Orthopaedic Clinic, University Hospital Olomouc (part-time job)
2015 – present
parental leave
Education and postgraduate training:
1997 – 2002
Faculty of Chemistry, Brno University of Technology, Brno (Ing.)
2002 – 2006
Faculty of Medicine and Dentistry, Palacký University, Olomouc (Ph.D.)
Membership:
2006
Scandinavian Society of Cell Toxicology
2009
Phytochemical Society of Europe
2004 – present
Czech Chemical Society
Teaching activites:
2002 – 2004
Medical chemistry (exercises and seminars for students of Medicine – in Czech; Faculty of Medicine, Palacký University Olomouc)
2003 – 2005
Biochemistry (exercises and seminars for students of Medicine – in Czech; Faculty of Medicine, Palacký University Olomouc)
2005 – present
Biochemistry (exercises and seminars for students of Dentistry – in Czech; Faculty of Medicine, Palacký University Olomouc)
2011 – present
Biochemistry (exercises and seminars for students of Dentistry – in English; Faculty of Medicine, Palacký University Olomouc)
2012 – present
Biochemistry (lectures for students of Dentistry – in English; Faculty of Medicine, Palacký University Olomouc)
2015 – present
Biochemistry (lectures for students of Dentistry – in Czech; Faculty of Medicine, Palacký University Olomouc)
Research Fellowships:
September 2003
Deutsches Krebsfordschungszentru (DKFZ), Heidelberg, Germany
March-May 2005
School of Health Science University of Wolverhampton, UK
April 2007
Institute of Pharmaceutical Biology and Pharmacology, Department of Molecular Cell Biology, Martin-Luther-University of Halle, Germany
November 2007
Institute of Pharmaceutical Biology and Pharmacology, Department of Molecular Cell Biology, Martin-Luther-University of Halle, Germany
June 2013
Kirkstall, Ltd., Faculty of Medicine, Dentistry and Health, The University of Sheffield, UK
Grant Projects (current):
2014-2017
Project TA 04010100 „Tribological coatings of enhanced corrosion protection for orthopedic and traumatology applications“.
Publications:
- Original papers (34)
- Review (5)
- 5 most important:
2016
Galandakova A, Frankova J, Ambrozova N, Habartova K, Pivodova V., Zalesak B, Safarova M, Smekalova M, Ulrichova J: Effects of silver nanoparticles on human dermal fibroblasts and epidermal keratinocytes. Human and Experimental Toxicology – in press
2016
Galandkova A, Ulrichova J, Langova K, Hanakova A, Vrbka M, Hartl M, Gallo J: Characteristics of synovial fluid required for optimization of lubrication fluid for biotribological experiments. Journal of biomedical materials research. Part B, Applied biomaterials. – in press
2013
Jelinek M, Kocourek T, Remsa J, Weiserova M, Jurek K, Miksovsky J, Strnad J, Galandkova A, Ulrichova J: Antibacterial, cytotoxicity and physical properties of laser — Silver doped hydroxyapatite layers. Materials science & engineering. C, Materials for biological applications, 33, p. 1242-1246, 2013.
2010
Zdarilova A, Rajnochova Svobodova A, Chytilova K, Simanek V, Ulrichova J: Polyphenolic fraction of Lonicera caerulea L. fruits reduces oxidative stress and inflammatory markers induced by lipopolysaccharide in gingival fibroblasts. Food and chemical toxicology, 48, p. 1555-1561, 2010.
2010
Zdarilova A, Svobodova A, Simanek V, Ulrichova J: Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts. Toxicology in vitro, 23, p. 386-392, 2009.
Recent Active and Invited Presentations (conferences, meetings):
- Sumary (75)
2015
Galandáková A., Šimánek V., Ulrichová J.: Polyphenolic fraction of Lonicera caerulea combined with alkaloid fraction of Macleaya cordata reduced LPS-induced inflammation in vitro. 8th International Workshop on Anthocyanins, 16.-18.9.2015, Motpellier, Francie.
2014
Ambrožová N., Galandáková A., Zálešák B., Ulrichová J.: The effects of silver nanoparticles on Nrf2 a NF-kB pathways in normal human dermal fibroblasts. XXIV. Biochemický zjazd, 18.-21.8.2014, Bratislava, Slovakia.
2013
Galandáková A., Franková J., Ulrichová J.: Anti-inflammatory responses of lipopolysaccharide-induced human skin fibroblasts upon exposure to gold nanoparticles. Nanosafety 2013, 20.-22.11.2013, Saarbrucken, Germany.
2012
Galandáková A., Franková J., Habartová K., Zálešák B., Ulrichová J.: Biological effects induced by silver and gold nanoparticles: In vitro study. Trends in NanoTechnology 2012, 10.9.-14.9.2012, Madrid, Spain.
2012
Galandáková A., Anzenbacherová E., Dvořáčková S., Ulrichová J.: Stanovení antioxidační kapacity slin. Inovace praktické výuky biochemie pro studenty zubního lékařství. XXIII. Biochemický sjezd, 26.-29.8.2012, Brno, Czech Republic.
Recent Awards:
Prize for student’s scientific publication awarded by Dean of Faculty of Medicine, Palacký University Olomouc for „Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.“ Food. Chem. Toxicol. 44, 242-9 (2006).