Ing. Adéla Galandáková, Ph.D.

Adéla Galandáková (Ing, PhD) (born Zdařilová)

 

Department of Medical Chemistry and Biochemistry

Hněvotínská 3

775 15 Olomouc, Czech Republic

e-mail: galandakova.a@seznam.cz

tel: +420 585 63 2325

 

Research Topics:

  • Biological activity of natural substances, plant extracts (in vitro and in vivo), silver and gold nanoparticles; antioxidant and anti-inflammatory activity; metabolic transformation; DNA damage; influence of joint fluid composition on lubricating film formation in total hip arthroplasty.
  • Cytotoxicity, inflammation, biological fluid, tribology

 

Position:

2005 – 2009                

Researcher, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University Olomouc

2009 – present

Assistant Professor, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University Olomouc

2013 – 2015

Junior researcher, Institute of Molecular and Translatione Medicine, Palacký University Olomouc

2013 – 2015

Science analyst-diagnosticians, Orthopaedic Clinic, University Hospital Olomouc (part-time job)

2014 – present

Technical co-worker, Orthopaedic Clinic, University Hospital Olomouc (part-time job)

2015 – present

parental leave

 

Education and postgraduate training:

1997 – 2002

Faculty of Chemistry, Brno University of Technology, Brno (Ing.)

2002 – 2006

Faculty of Medicine and Dentistry, Palacký University, Olomouc (Ph.D.)

 

Membership:

2006

Scandinavian Society of Cell Toxicology

2009                           

Phytochemical Society of Europe

2004 – present                       

Czech Chemical Society

 

Teaching activites:

2002 – 2004

Medical chemistry (exercises and seminars for students of Medicine – in Czech; Faculty of Medicine, Palacký University Olomouc)

2003 – 2005

Biochemistry (exercises and seminars for students of Medicine – in Czech; Faculty of Medicine, Palacký University Olomouc)

2005 – present

Biochemistry (exercises and seminars for students of Dentistry – in Czech; Faculty of Medicine, Palacký University Olomouc)

2011 – present

Biochemistry (exercises and seminars for students of Dentistry – in English; Faculty of Medicine, Palacký University Olomouc)

2012 – present

Biochemistry (lectures for students of Dentistry – in English; Faculty of Medicine, Palacký University Olomouc)

2015 – present

Biochemistry (lectures for students of Dentistry – in Czech; Faculty of Medicine, Palacký University Olomouc)

 

Research Fellowships:

September 2003

Deutsches Krebsfordschungszentru (DKFZ), Heidelberg, Germany

March-May 2005

School of Health Science University of Wolverhampton, UK

April 2007

Institute of Pharmaceutical Biology and Pharmacology, Department of Molecular Cell Biology, Martin-Luther-University of Halle, Germany

November 2007

Institute of Pharmaceutical Biology and Pharmacology, Department of Molecular Cell Biology, Martin-Luther-University of Halle, Germany

June 2013

Kirkstall, Ltd., Faculty of Medicine, Dentistry and Health, The University of Sheffield, UK

 

Grant Projects (current):

2014-2017

Project TA 04010100 „Tribological coatings of enhanced corrosion protection for orthopedic and traumatology applications“.

 

Publications:

  • Original papers (34)
  • Review (5)

 

  • 5 most important:

2016                          

Galandakova A, Frankova J, Ambrozova N, Habartova K, Pivodova V., Zalesak B, Safarova M, Smekalova M, Ulrichova J: Effects of silver nanoparticles on human dermal fibroblasts and epidermal keratinocytes. Human and Experimental Toxicology – in press

2016

Galandkova A, Ulrichova J, Langova K, Hanakova A, Vrbka M, Hartl M, Gallo J: Characteristics of synovial fluid required for optimization of lubrication fluid for biotribological experiments. Journal of biomedical materials research. Part B, Applied biomaterials. – in press

2013

Jelinek M, Kocourek T, Remsa J, Weiserova M, Jurek K, Miksovsky J, Strnad J, Galandkova A, Ulrichova J: Antibacterial, cytotoxicity and physical properties of laser — Silver doped hydroxyapatite layers. Materials science & engineering. C, Materials for biological applications, 33, p. 1242-1246, 2013.

2010

Zdarilova A, Rajnochova Svobodova A, Chytilova K, Simanek V, Ulrichova J: Polyphenolic fraction of Lonicera caerulea L. fruits reduces oxidative stress and inflammatory markers induced by lipopolysaccharide in gingival fibroblasts. Food and chemical toxicology, 48, p. 1555-1561, 2010.

2010

Zdarilova A, Svobodova A, Simanek V, Ulrichova J: Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts. Toxicology in vitro, 23, p. 386-392, 2009.

 

Recent Active and Invited Presentations (conferences, meetings):

  • Sumary (75)

 

2015               

Galandáková A., Šimánek V., Ulrichová J.: Polyphenolic fraction of Lonicera caerulea combined with alkaloid fraction of Macleaya cordata reduced LPS-induced inflammation in vitro. 8th International Workshop on Anthocyanins, 16.-18.9.2015, Motpellier, Francie.

2014

Ambrožová N., Galandáková A., Zálešák B., Ulrichová J.: The effects of silver nanoparticles on Nrf2 a NF-kB pathways in normal human dermal fibroblasts. XXIV. Biochemický zjazd, 18.-21.8.2014, Bratislava, Slovakia.

2013

Galandáková A., Franková J., Ulrichová J.: Anti-inflammatory responses of lipopolysaccharide-induced human skin fibroblasts upon exposure to gold nanoparticles. Nanosafety 2013, 20.-22.11.2013, Saarbrucken, Germany.

2012

Galandáková A., Franková J., Habartová K., Zálešák B., Ulrichová J.: Biological effects induced by silver and gold nanoparticles: In vitro study. Trends in NanoTechnology 2012, 10.9.-14.9.2012, Madrid, Spain.

2012

Galandáková A., Anzenbacherová E., Dvořáčková S., Ulrichová J.: Stanovení antioxidační kapacity slin. Inovace praktické výuky biochemie pro studenty zubního lékařství. XXIII. Biochemický sjezd, 26.-29.8.2012, Brno, Czech Republic.

 

Recent Awards:

Prize for student’s scientific publication awarded by Dean of Faculty of Medicine, Palacký University Olomouc for „Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.“ Food. Chem. Toxicol. 44, 242-9 (2006).