Jiří Vrba (Assoc. Prof., PhD, MSc.)
Department of Medical Chemistry and Biochemistry
Hněvotínská 3
775 15 Olomouc, Czech Republic
e-mail: j.vrba@upol.cz
tel: +420 585 63 2310
Research Topics:
- Molecular toxicology and pharmacology; Biological activity of low molecular weight compounds
- Natural and synthetic compounds; Biological interactions; Biotransformation
Position:
2017
Associate Professor, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Olomouc
Education and employment:
From 2017
Associate Professor, Palacky University, Olomouc
2012 – 2017
Assistant Professor, Palacky University, Olomouc
2004 – 2011
Research Assistant, Palacky University, Olomouc
2001 – 2005
PhD study, Palacky University, Olomouc
1996 – 2001
Analyst, Tekro Ltd, Prague
1990 – 1995
MSc study, Palacky University, Olomouc
Teaching activites:
Biochemistry (Faculty of Medicine and Dentistry, Faculty of Health Sciences, Palacky University, Olomouc)
Research Fellowships:
2005
Sanofi Aventis, Vitry sur Seine, France
2009
University of Texas M. D. Anderson Cancer Center, Houston, USA
Recent publications:
- Vrba J., Zapletalová V., Havlásek J., Papoušková B., Petránková B., Pelantová H., Valentová K. Sulfation rewrites the biological profile of dietary flavonoids: Implications for stability, redox signaling, and inflammation. Food Science & Nutrition 14(9), art. no. e72382 (2026).
- Vrba J., Havlasek J., Dostalova K., Rysava A., Zapletalova V., Papouskova B., Zalesak B., Storch J., Vacek J. Cannabigerol and cannabidiol differ in their ability to affect the AhR/CYP1A pathway in vitro. Food and Chemical Toxicology 214, art. no. 116156 (2026).
- Zatloukalova M., Fabre G., Jedinak L., Pospíšil J., Dziubak D., Pavićević A., Dostal Z., Vrba J., Sek S., Mojović M., Trouillas P., Vacek J. Lipid membrane behavior of nitro-fatty acids and their loading into liposomes to activate Nrf2 pathway in RAW264.7 cells with impact on intracellular NO production. Chemistry and Physics of Lipids 270, art. no. 105497 (2025).