Denisa Škařupová (Gerhardová) (MSc.)
Department of Medical Chemistry and Biochemistry
Hněvotínská 3
775 15 Olomouc, Czech Republic
e-mail: DenisaGerhardova@seznam.cz
Research Topics:
- Oxidative stress, UV radiation, phototoxic and photoprotective effect of natural compound, melanogenesis
- skin explants, skin cell cultures: fibroblasts (NHDF), keratinocytes (HaCaT, NHEK), melanocytes (NHEM, B16-F10), cocultures
Position:
2019 – Present
PhD, Department of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacký University, Olomouc
Education and postgraduate training:
2015 – 2018
Maternity leave
2014 – 2015
PhD, Department of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacký University, Olomouc
2012 – 2014
Master`s Degree, Biochemistry, Faculty of Science, Palacký University, Olomouc
2008 – 2012
Bachelor`s Degree, Biochemistry, Faculty of Science, Palacký University, Olomouc
Work experiences:
2015 (6 months)
Contipro a.s., Dolní Dobrouč, Czech Republic – Assistant Specialist
2010 (3 weeks)
Pharmaceutical Control Laboratory, Army Czech Republic, Bystřice pod Hostýnem
Teaching activites:
2014
Medical chemistry (Faculty of Medicine, Palacký University Olomouc)
Membership:
2020
Czech Society for Biochemistry and Molecular Biology
Publications:
2014
Vrba J., Havlikova M., Gerhardova D., Ulrichova J.
Palmatine activates AhR and upregulates CYP1A activity in HepG2 cells but not in human hepatocytes.
Toxicol. In Vitro 28 (4), 693-699 (2014)
Recent Active and Invited Presentations:
2019
XX. Meeting of biochemists and molecular biologists, Brno, Czech Republic
Abstract: UVA protective activity of silymarin and silybin in skin explants model. Škařupová D., Vostálová J., Rajnochová A., Ulrichová J., Zálešák B.
2015
XVII. Meeting of biochemists and molecular biologists, Brno, Czech Republic
Abstract: Comparison of melanoma and keratinocyte cocultures as a model for
studying pigmentation. Gerhardová D., Vostálová J., Rajnochová A., Ulrichová J.,
Moravcová M., Muthný T.
2014
XVI. Meeting of biochemists and molecular biologists, Brno, Czech Republic
Abstract: Modulation of skin cells by UVA radiation. Gerhardová D., Rajnochová A., Vostálová J., Ulrichová J.
Awards:
2015
Rector´s Award for the best student research work in biomedicine.
Effect of palmatine on the expression of cytochrome P450 1A1.