Mgr. Zdeněk Dostál, Ph.D.

Zdeněk Dostál (PhD, MSc.)

Department of Medical Chemistry and Biochemistry

Hněvotínská 3

775 15 Olomouc, Czech Republic

e-mail: zjedna@post.cz

tel: +420 585 63 2324

 

Research Topics:

  • Research topic is influence of selected polyphenols on microRNA expression in HepG2 cells and primary hepatocytes. Another field of interest is study of hsa-miR-29b effects on toxicity of etoposide and its mechanism.
  • miRNA, RT, RT-PCR, polyphenols, transfections, cell cultures, cytotoxicity

 

Position:

2019 – present

Assistant professor, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Olomouc

2014 – 2019             

researcher, Department of Medical Chemistry and Biochemistry/ Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University, Olomouc

 

Education and postgraduate training:

2013 – 2019

Ph.D. Study, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic

Dissertation thesis: Modulation of Xenobiotics Cytotoxicity.

Supervisor: Prof. Mgr. Martin Modrianský, Ph.D.

2011 – 2013

Master Study, Bioorganic chemistry, Faculty of Science, Palacký University, Olomouc, Czech Republic.

Diploma thesis: Influence of natural substances on microRNA expression in HepG2 cells.

Supervisor: Doc. Mgr. Martin Modrianský, Ph.D.

2008 – 2011

Bachelor Study, Bioorganic chemistry, Faculty of Science, Palacký University, Olomouc, Czech Republic.

Bachelor thesis: Role of apoptosis in microRNA release into serum.

Supervisor: Doc. Mgr. Martin Modrianský, Ph.D

 

Membership:
2018 – present

Czech Society for Biochemistry and Molecular Biology

2020 – present

Czech Chemical Society

 

Teaching activities:

2020 – present

Biochemistry II (Faculty of Medicine and Dentistry, Palacký University Olomouc)

2017 – present

Biochemistry I (Faculty of Medicine and Dentistry, Palacký University Olomouc)

2013 – present

Bioorganic chemistry (Faculty of Medicine and Dentistry, Palacký University Olomouc)

2013 – 2019

Medical chemistry (Faculty of Medicine and Dentistry, Palacký University Olomouc)

 

Research Fellowships:

2015

University of Padova, Padova, Italy (3 months)

 

Grant Projects:

2014 – 2017               

NPU – Podpora udržitelnosti Ústavu molekulární a translační medicíny (LO1304)

2015

IGA_LF_2016_012


Recent Active and Invited Presentations:

  • summary XI. DDPEO, X. DDPEO, XIV. Mezioborové setkání mladých biologů, biochemiků a chemiků, IX. DDPEO

 

  • last 5 years:

2020

72. Sjezd českých a slovenských chemických společností

2019

The 44th FEBS Congress

2018

XIV. Diagnostic Predictive and Experimental Oncology Days

The 43th FEBS Congress

2017

XXIX. Xenobiochemické symposium

2016

XII. Diagnostic Predictive and Experimental Oncology Days

 

Recent Awards:

2013 – IX. DDPEO conference – the best poster presentation