Vlastimil Dorčák (PhD, MSc.)
Contact:
Department of Medical Chemistry
and Biochemistry
Hněvotínská 3
775 15 Olomouc
Czech Republic
e-mail: vlastimil.dorcak@upol.cz
Research Topics:
- Bioanalytical and Biophysical Chemistry; Electrochemistry, Chemical Reactivity and Acido‑Basic Properties of Peptides and Proteins; Interactions of Peptides and Proteins with Charged Surfaces; Analytical and Fundamental Aspects of Peptide and Protein Electrode Reactions; Hydrogen Evolution Catalysed by Peptides and Proteins; Peptide and Protein Label-free and Structure-sensitive Analysis.
Position:
2023 – present
researcher – Department of Medical Chemistry and Biochemistry/ Institute of Molecular and Translational Medicine, Faculty of Medicine, Palacky University, Olomouc
2012 – 2020
researcher – Department of Biophysical Chemistry and Molecular Oncology, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic
2006 – 2008
postdoctoral fellow – Department of Biophysical Chemistry and Molecular Oncology, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic
2003 – 2006
research assistant – Department of Biophysical Chemistry and Molecular Oncology, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic
Education and Postgraduate Training:
1999 – 2002
PhD. at Department of Chemistry; Faculty of Agrobiology, Food and Natural Resources; Czech University of Life Sciences Prague; Czech Republic
Doctoral Thesis: Use of electrochemical methods for studying plant metallothioneins and their complexes with selected heavy metals.
1993 – 1999
Mgr. (degree equivalent to MSc.) at Faculty of Science, Pavol Jozef Šafárik University in Košice, Slovakia
Diploma Thesis: Contribution to the river monitoring by determination of heavy metals in fish muscle tissue using differential pulse anodic stripping voltammetry.
SELECTED PUBLICATIONS
Review articles
Sęk S., Vacek J. and Dorčák V. Electrochemistry of peptides, Current Opinion in Electrochemistry 14:166-172 (2019).
Paleček E., Heyrovský M. and Dorčák V.: J. Heyrovský’s Oscillographic Polarography. Roots of Present Chronopotentiometric Analysis of Biomacromolecules, Electroanalysis 2018, 30, 1259-1270.
Paleček E. and Dorčák V.: Lable-free electrochemical analysis of biomacromolecules,
Applied Materials Today 2017, 9, 434-450.
Original research papers
Paleček E. and Dorčák V.: Catalytic Deuterium Evolution and H/D Exchange in DNA, ChemElectroChem 2019, 6, 1032-1039.
Dorčák V., Novák D., Kabeláč M., Kroutil O., Bednárová L., Veverka V. and Vacek J.: Structural Stability of Peptidic His-Containing Proton Wire in Solution and in the Adsorbed State, Langmuir 2018, 34, 6997-7005.
Trefulka M., Dorčák V., Křenková J., Foret F. and Paleček E.: Electrochemical analysis of Os(VI)-modified glycoproteins and label-free glycoprotein detection eluted from lectin capillary column, Electrochimica Acta 2017, 239, 10-15.
Dorčák V., Kabeláč M., Kroutil O., Bednářová K. and Vacek J.: Electrocatalytic monitoring of peptidic proton-wires, Analyst 2016, 141, 4554-4557.
Dorčák V., Ostatná V. and Paleček E.: Electrochemical reduction and oxidation signals of angiotensin peptides. Role of individual amino acid residues, Electrochemistry Communications 2013, 31, 80-83.