Jakub Havlásek (MSc.)
Department of Medical Chemistry and Biochemistry
Hněvotínská 3
775 15 Olomouc, Czech Republic
e-mail: jak.havlasek@seznam.cz
tel: +420 585 63 2304
Research Topics:
- biological activity of natural compounds, biotransformation
- transcription factor Nrf2, oxidative stress, cell cultures
Position:
2021 – present
Postgradual student, Department of Medical Chemistry and Biochemistry
Education:
2021 – present
Ph.D. Study, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic
2015 – 2018
Master Study, Experimental biology, Faculty of Science, Palacký University, Olomouc, Czech Republic.
2012 – 2015
Bachelor Study, Molecular biology, Faculty of Science, Palacký University, Olomouc, Czech Republic.
Teaching activities:
2021 – present
Medical chemistry (Faculty of Medicine and Dentistry, Palacký University Olomouc)
Grant projects:
IGA_LF_2019_025 Mechanismy lékové resistence u nádorových buněk
IGA_LF_2020_025 Multiformní glioblastom a mechanismy lékové rezistence
GAČR (grantový projekt č. 17-16614S), 2018 – 2020
Publications:
Pastvova N., Havlasek J., Dolezel P., Kikalova K., Studentova H., Zemankova A., Melichar B., Mlejnek P. Changes in expression of lysosomal membrane proteins in leucocytes of cancer patients treated with tyrosine kinase inhibitors. Cancer Chemother Pharmacol. 2021, published online, doi: 10.1007/s00280-021-04266-6.
Mlejnek P., Havlasek J., Pastvova N., Dolezel P. Can image analysis provide evidence that lysosomal sequestration mediates daunorubicin resistance? Chem Biol Interact. 2020, 327:109138, doi: 10.1016/j.cbi.2020.109138.