Mgr. Jakub Havlásek

Jakub Havlásek (MSc.)

Department of Medical Chemistry and Biochemistry

Hněvotínská 3

775 15 Olomouc, Czech Republic

e-mail: jak.havlasek@seznam.cz

tel: +420 585 63 2304

 

Research Topics:

  • biological activity of natural compounds, biotransformation
  • transcription factor Nrf2, oxidative stress, cell cultures

 

Position:

2021 – present

Postgradual student, Department of Medical Chemistry and Biochemistry

 

Education:

2021 – present

Ph.D. Study, Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czech Republic

2015 – 2018

Master Study, Experimental biology, Faculty of Science, Palacký University, Olomouc, Czech Republic.

2012 – 2015

Bachelor Study, Molecular biology, Faculty of Science, Palacký University, Olomouc, Czech Republic.

 

Teaching activities:

2021 – present

Medical chemistry (Faculty of Medicine and Dentistry, Palacký University Olomouc)

 

Grant projects:

IGA_LF_2019_025 Mechanismy lékové resistence u nádorových buněk

IGA_LF_2020_025 Multiformní glioblastom a mechanismy lékové rezistence

GAČR (grantový projekt č. 17-16614S), 2018 – 2020

 

Publications:

Pastvova N., Havlasek J., Dolezel P., Kikalova K., Studentova H., Zemankova A., Melichar B., Mlejnek P. Changes in expression of lysosomal membrane proteins in leucocytes of cancer patients treated with tyrosine kinase inhibitors. Cancer Chemother Pharmacol. 2021, published online, doi: 10.1007/s00280-021-04266-6.

Mlejnek P., Havlasek J., Pastvova N., Dolezel P. Can image analysis provide evidence that lysosomal sequestration mediates daunorubicin resistance? Chem Biol Interact. 2020, 327:109138, doi: 10.1016/j.cbi.2020.109138.