Mgr. Daniel Karas

Daniel Karas (MSc.)

Department of Medical Chemistry and Biochemistry

Hněvotínská 3

775 15 Olomouc, Czech Republic

e-mail: karasd@seznam.cz

tel: +420 585 63 2304

 

Research Topics:

  • Effect of natural compounds and their semi-synthetic derivatives on angiogenesis and apoptosis
  • Cell cultures (HUVECs, fibroblasts, tumor cell lines), in vitro methods, electrophoresis, western blotting

 

Position:

2014 – present           

Researcher, Department of Medical Chemistry and Biochemistry/ Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc

 

Education and postgraduate training:

2012 – present

Ph.D. student – Dept. of Medical Chemistry and Biochemistry, Palacky University Olomouc

2010 – 2012

Master´s degree in Biochemistry, Palacky University Olomouc

2007 – 2010

Bachelor´s degree in Biochemistry, Palacky University Olomouc

2003 – 2007

Grammar school, Hlučín

 

Membership:

2016 – present

Czech Chemical Society

2015 – present                       

Czech Society for Biochemistry and Molecular Biology

 

Teaching activites:

2012 – present

Biochemistry (Faculty of Medicine and Dentistry, Palacky University Olomouc)

2013 – present

Medical chemistry (Faculty of Medicine and Dentistry, Palacky University Olomouc)

 

Research Fellowships:

2013 (three months)

Laboratory for Therapeutic Innovation, Strasbourg, France

2014 (two months)

Laboratory for Therapeutic Innovation, Strasbourg, France

 

Grant Projects:

2016 – 2017               

IGA_LF_2016_012

2014 – 2019

LO1304 – Support of suistainability of the Institute of Molecular and Translational Medicine (2014-2019, MSM/LO)

 

Publications:

2015               

Minker C, Duban L, Karas D, Järvinen P, Lobstein A, Muller C D: Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer. Oxidative Medicine and Cellular Longevity, vol. 2015, Article ID 154164, 13 pages, 2015. doi:10.1155/2015/154164.

 

Recent Active and Invited Presentations:

2015                          

Karas D, Pivodová V, Valentová K, Křen V, Lobstein A, Muller C D, Ulrichová J: Effect of natural compounds and their semi-synthetic derivatives on apoptosis and angiogenesis. Spetses Summer School, a FEBS advanced lecture course, Molecular Mechanisms in Signal Transduction and Cancer, 16. 8. – 24. 8. 2015, Spetses, Řecko.

Pivodová V, Zahler S, Karas D, Křen V, Ulrichová J: The effect of 7-O-galloyl-dehydrosilybin on filopodia of endothelial cells. 9th World Congress on Polyphenols Applications, 3. 6. – 5. 6. 2015, ISBN 978-2-35609-073-7, p. 168, St Julian´s, Malta.

2014

Karas D, Křen V, Valentová K., Lobstein A, Muller C D, Ulrichová J: The effect of natural compounds and their synthetic derivatives on apoptosis of THP-1 cells. XXIV. Biochemický zjazd SSBMB a ČSBMB,  18. 9. – 21. 9. 2014, ISBN 978-80-970164-6-3, p. 160-161, Bratislava, Slovensko.

2013

Karas D, Gažák R, Křen V, Oborná I, Ulrichová J.., Valentová K: Dehydrosilybin and its galloylderivatives as modulators of angiogenesis. The Student Scientific conference on biotechnology and biomedicine, 10. 4. – 12. 4. 2013,  ISBN 978-80-210-6200-9, p. 144, Brno, Česká republika.

Valentová K, Nabergoj D, Vrbek S, Lobstein A, Muller C D, Ulrichová J, Karas D, Křen V: Vliv flavonoidů a jejich galátů na indukci apoptosy lidských buněčných linií. Konference vědeckých prací studentů DSP, 16. 12. – 17. 12. 2013,  p. 30, Olomouc, Česká republika.